Fertility achieved through in vitro fertilization in a male patient with 48,XXYY syndrome

نویسندگان

  • De-Feng Liu
  • Lian-Ming Zhao
  • Kai Hong
  • Jia-Ming Mao
  • Yu-Zhuo Yang
  • Zhe Zhang
  • Hui Jiang
چکیده

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Chromosome 2 fragility- 48, XXYY syndrome

We report a case of double male syndrome, a type of Klinefelter syndrome with 48, XXYY chromosome. The case had been referred to our department because of severe mental retardation and behavioural and psychiatric problems. In the karyotype analysis, the chromosome constitution of that 16–year–old case was revealed as 48, XXYY, fra 2q (32.2–32.3). More than 70 patients with 48, XXYY chromosome c...

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XYY syndrome, and XYY-XXYY mosaicism also showing features of Klinefelter's syndrome.

Both the 48,XXYY and the 47,XYY chromosome anomalies are now well-recognized conditions following the first reports by Muldal and Ockey (1960) of the XXYY genotype, and Sandberg et al. (1961) who described an XYY male. This paper presents the findings in 2 patients with 47,XYY/48,XXYY mosaicism, and one patient with the 47,XYY anomaly, discovered among 250 men in a comprehensive hospital for th...

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عنوان ژورنال:

دوره 20  شماره 

صفحات  -

تاریخ انتشار 2018